GLP-1 Medication and PCOS
GLP-1 Injections: A Promising New Treatment for PCOS
Introduction
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women of reproductive age. Characterized by irregular menstrual cycles, hyperandrogenism, and polycystic ovaries, PCOS often leads to significant metabolic complications, including insulin resistance, obesity, and an increased risk of type 2 diabetes. GLP-1 medication has recently emerged as a promising treatment for patients with PCOS.
Understanding PCOS and Its Metabolic Challenges
PCOS is not only a reproductive disorder but also a metabolic one. Women with PCOS often experience:
Insulin Resistance: A significant majority of women with PCOS have insulin resistance, which can lead to type 2 diabetes if not managed effectively. By activating GLP-1 receptors, GLP-1 injections enhance insulin sensitivity, helping to lower blood glucose levels and mitigate insulin resistance.
Obesity: Weight gain and difficulty losing weight are common challenges due to metabolic inefficiencies and hormonal imbalances. GLP-1 medications cause weight loss. Weight reduction can improve ovulatory function and reduce hyperandrogenism.
Hyperandrogenism: Elevated levels of androgens can cause symptoms like hirsutism (excess hair growth), acne, and alopecia. By addressing the underlying metabolic issues, GLP-1 medication can help lower androgen levels, reducing symptoms like hirsutism and acne.
Cardiovascular Risk: The metabolic disturbances associated with PCOS increase the risk of cardiovascular diseases. GLP-1 medication has been associated with improvements in cardiovascular risk markers
Decreased Fertility: PCOS causes menstrual irregularities and metabolic imbalances that can affect fertility. Weight loss and improved insulin sensitivity can enhance ovulatory function, increasing the chances of conception for women with PCOS.
Important information to Remember: Pregnancy while taking a GLP-1 medication is not recommend. You must use contraception while on GLP-1 medication and for a period of time after discontinuation. Our providers will discuss this with you in detail at your initial consult.